Phylogeny of the Insect Homeobox Gene (Hox) Cluster
نویسندگان
چکیده
منابع مشابه
Phylogeny of the Insect Homeobox Gene (Hox) Cluster
The homeobox (Hox) genes form an evolutionarily conserved family encoding transcription factors that play major roles in segmental identity and organ specification across species. The canonical grouping of Hox genes present in the HOM-C cluster of Drosophila or related clusters in other organisms includes eight "typical" genes, which are localized in the order labial (lab), proboscipedia (pb), ...
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Hox and other Antennapedia (ANTP)-like homeobox gene subclasses - ParaHox, EHGbox, and NK-like - contribute to key developmental events in bilaterians [1-4]. Evidence of physical clustering of ANTP genes in multiple animal genomes [4-9] suggests that all four subclasses arose via sequential cis-duplication events. Here, we show that Hox genes' origin occurred after the divergence of sponge and ...
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We have characterized Hox 1.3 (previously described as m2), a murine homeobox-containing gene, which is a member of the Hox 1 cluster located on chromosome 6. A cloned cDNA was isolated from an Okayama-Berg library generated from the chemically transformed cell line MB66 MCA ACL6. The protein sequence of 270 amino acids was deduced from the nucleotide sequence of an open reading frame containin...
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Many of the genes controlling segmentation and pattern formation in Drosophila contain a conserved 183 bp sequence known as the homeobox. Homeobox sequences have been found in a range of metazoan species, including the vertebrates mouse and man. This striking conservation suggests that homeobox genes may play a fundamental role in developmental processes. If this is the case then it might be ex...
متن کاملOrganization of an echinoderm Hox gene cluster.
The Strongylocentrotus purpuratus genome contains a single ten-gene Hox complex >0.5 megabase in length. This complex was isolated on overlapping bacterial artificial chromosome and P1 artificial chromosome genomic recombinants by using probes for individual genes and by genomic walking. Echinoderm Hox genes of Paralog Groups (PG) 1 and 2 are reported. The cluster includes genes representing al...
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ژورنال
عنوان ژورنال: Genomics, Proteomics & Bioinformatics
سال: 2005
ISSN: 1672-0229
DOI: 10.1016/s1672-0229(05)03006-8